oligonucleotide|oligonucleotides in English
noun
short chain of up to 20 nucleotides
Use "oligonucleotide|oligonucleotides" in a sentence
1. An oligonucleotide encoding a gene which is capable of regulating the synthesis of abscisic acid and encoding an amino acid sequence consisting of from M at the 1-position to I at the 164-position of the amino acids in the sequence represented by SEQ ID NO:2 in Sequence Listing, or oligonucleotides containing an oligonucleotide encoding an amino acid sequence derived from the above-described amino acid sequence by deletion, substitution or addition of one or several amino acids; products of these oligonucleotides; and vectors and plants containing these oligonucleotides.
2. Antisense oligonucleotides for spinocerebellar Ataxias
3. Pharmaceutical compounds comprising abasic oligonucleotides
4. Also provided are conjugates between abasic oligonucleotides and various immunostimulatory nucleic acids, including CpG oligonucleotides, as well as methods of use thereof.
5. We have developed a second-generation Antisense oligonucleotide (ISIS 25302) specific for murine TNF-alpha and have evaluated this oligonucleotide in …
6. We have shown that the splicing of a refractory exon, SMN2 exon 7, could be increased in fibroblasts derived from patients with spinal muscular atrophy by using Bifunctional targeted oligonucleotide enhancers of splicing (TOES) oligonucleotides that anneal to the exon and …
7. Antisense oligonucleotide-based therapeutics involves downregulation of gene expression
8. The adaptor may be a cholesterol-linked DNA adapter oligonucleotide.
9. Stretch-activated cation channel and antisense oligonucleotides thereto
10. Bio-Synthesis offers dSpacer Abasic oligonucleotide modification at various scales
11. Antisense oligonucleotides (ASOs) are short oligonucleotides that localize to the nucleus and provide a pathway for gene silencing by the RNase H pathway
12. Immunostimulatory compositions comprising liposome-encapsulated oligonucleotides as active ingredients
13. DSpacer is commonly used to mimic an Abasic site in an oligonucleotide
14. Adaptor A short synthetic oligonucleotide which creates an internal restriction endonuclease site
15. 13 The double-stranded oligonucleotide was then purified by polyacrylamide gel electrophoresis.
16. These oligonucleotides thus comprise a therapeutic potential for treating pancreatic tumors.
17. Avidity is pioneering a new class of oligonucleotide-based therapies called AOCs designed to overcome the current limitations of oligonucleotide therapies in order to treat a wide range of serious diseases.
18. In this review we will focus on the mechanisms of action of Antisense oligonucleotides
19. Oligonucleotides are transferred in the cells under the influence of shock waves.
20. Avidity Biosciences is pioneering a new class of oligonucleotide-based therapies called AOCs designed to overcome the current limitations of oligonucleotide-based therapies in order to treat a wide range of serious diseases.
21. Antisense oligonucleotides are synthetic stretches of DNA which hybridize with specific mRNA strands
22. The experimental drug, Ionis-HTTRx, is a type of drug called “Antisense oligonucleotides”
23. The Azides are offered in 25 and 100 µmole packs for convenient oligonucleotide labeling
24. Oligonucleotides are disclosed that have increased binding affinity as shown by molecular modeling experiments.
25. The A-form geometry imparts properties to the oligonucleotide that modulate binding affinity and nuclease resistance.